NEOS Formulary Searchable neonatal drug formulary with dosing guidelines, maximum doses, side effects, and clinical notes. Search by name or filter by category.
Disclaimer
This formulary was created based on the latest medical updates. However, it is not a replacement for your hospital or official governmental health agencies' policies. Always refer to your hospital protocols and MOH guidelines.
All (47) Aminoglycoside (3) Antibiotic (13) Antifungal (5) Antiviral (3) Prostaglandin (4) Antiarrhythmic (2) Diuretic (3) Muscle Relaxant (2) Sedative (5) Inotropic Agent (3) Vasopressor (4)
Showing 47 of 47 medications
Aminoglycoside(3) Amikacin 15 mg/kg/dose every 12 hours for PMA <30 weeks; 20 mg/kg/dose every 8 hours for PMA >30 weeks
Gentamicin 4-5 mg/kg/dose every 24-48 hours depending on PMA and postnatal age
Tobramycin 4-5 mg/kg/dose every 24-48 hours depending on PMA and postnatal age
Antiarrhythmic(2) Adenosine Initial: 0.05-0.1 mg/kg rapid IV push; increase by 0.05 mg/kg every 2 minutes
Amiodarone Loading: 5 mg/kg IV over 30-60 minutes; Maintenance: 5-15 mcg/kg/min continuous infusion
Antibiotic(13) Amoxicillin 20-30 mg/kg/day divided every 12 hours
Amoxicillin-Clavulanic Acid (Augmentin) 30 mg amoxicillin/kg/day divided every 12 hours
Ampicillin 200-300 mg/kg/day divided every 8 hours for GBS Meningitis; 50 mg/kg/dose q8-12h for sepsis
Azithromycin 10 mg/kg once daily
Aztreonam 30 mg/kg/dose every 12 hours for neonates
Cefotaxime 50 mg/kg/dose every 8-12 hours; meningitis: every 6-8 hours
Ceftazidime 50 mg/kg/dose every 8-12 hours
Clindamycin 5-7.5 mg/kg/dose every 8-12 hours
Meropenem 20-40 mg/kg/dose every 8-12 hours; meningitis: 40 mg/kg/dose every 8 hours
Metronidazole Loading: 15 mg/kg; Maintenance: 7.5 mg/kg/dose every 12-24 hours
Piperacillin-Tazobactam 75-100 mg piperacillin/kg/dose every 8-12 hours based on gestational age
Vancomycin 10-15 mg/kg/dose every 8-24 hours based on PMA and renal function
Caffeine Citrate Loading: 20 mg/kg IV/PO; Maintenance: 5-10 mg/kg/day once daily
Antifungal(5) Amphotericin B 3-5 mg/kg/dose once daily
Amphotericin B Lipid Complex (Abelcet) 3-5 mg/kg/dose once daily
Amphotericin B Liposomal (AmBisome) 3-5 mg/kg/day once daily
Fluconazole Prophylaxis: 3-6 mg/kg twice weekly; Treatment: 12 mg/kg loading then 6 mg/kg/day
Micafungin 4-10 mg/kg/day once daily
Antiviral(3) Acyclovir 20 mg/kg/dose IV every 8 hours for HSV disease
Ganciclovir Induction: 6 mg/kg/dose IV every 12 hours for 6 weeks; Maintenance: 6 mg/kg/dose once daily
Valganciclovir 16 mg/kg/dose oral twice daily
Diuretic(3) Furosemide IV: 1-2 mg/kg/dose every 12-24 hours; Oral: 1-4 mg/kg/dose
Chlorothiazide 10-20 mg/kg/dose every 12 hours (oral)
Spironolactone 1-3 mg/kg/day divided every 12-24 hours
Inotropic Agent(3) Dopamine 2-20 mcg/kg/min continuous infusion; Low dose (renal): 2-5; Medium (cardiac): 5-10; High (vasopressor): 10-20
Dobutamine 2-20 mcg/kg/min continuous infusion
Milrinone Loading: 50 mcg/kg over 15-60 minutes (optional); Maintenance: 0.25-0.75 mcg/kg/min
Muscle Relaxant(2) Cisatracurium 0.1-0.2 mg/kg IV bolus; Infusion: 0.5-3 mcg/kg/min
Vecuronium 0.1 mg/kg IV bolus; Infusion: 0.05-0.1 mg/kg/hr
Prostaglandin(4) Alprostadil (Prostaglandin E1) Initial: 0.05-0.1 mcg/kg/min; Maintenance: 0.01-0.05 mcg/kg/min
Indomethacin PDA closure: Initial 0.2 mg/kg IV, then 0.1-0.25 mg/kg every 12-24 hours x 2 additional doses
Ibuprofen Lysine PDA closure: Initial 10 mg/kg IV, then 5 mg/kg at 24h and 48h
Acetaminophen (Paracetamol) PDA closure: 15 mg/kg/dose IV/PO every 6 hours for 3-7 days; Analgesia: 10-15 mg/kg/dose q6-8h
Sedative(5) Midazolam Sedation: 0.05-0.15 mg/kg IV; Infusion: 0.5-2 mcg/kg/min; Intranasal: 0.2 mg/kg
Fentanyl Bolus: 1-4 mcg/kg IV; Infusion: 1-5 mcg/kg/hr; Intubation: 2-4 mcg/kg
Morphine Bolus: 0.05-0.1 mg/kg IV; Infusion: 10-40 mcg/kg/hr; Preterm: 0.025 mg/kg
Dexmedetomidine Loading: 0.5 mcg/kg over 10 minutes (optional); Infusion: 0.2-0.7 mcg/kg/hr
Phenobarbital Seizures loading: 20-40 mg/kg IV; Maintenance: 3-5 mg/kg/day divided q12-24h
Vasopressor(4) Epinephrine (Adrenaline) Infusion: 0.01-1 mcg/kg/min; Cardiac arrest: 0.01-0.03 mg/kg IV/IO (1:10,000); ETT: 0.05-0.1 mg/kg
Norepinephrine (Noradrenaline) 0.01-0.5 mcg/kg/min continuous infusion
Vasopressin 0.0001-0.002 units/kg/min continuous infusion
Hydrocortisone (Vasopressor dose) Refractory hypotension: 1-2 mg/kg/dose IV q6-8h; Stress dose: 30-50 mg/m2/day